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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
A final combination form of medications is often required to treat specific conditions, including erectile dysfunction and pulmonary arterial hypertension. However, like all medications, it may interact with other medications you are taking, including other diuretics and medications for high blood pressure. pioneered the development of Cialis
  1. 1950: A heart-healthy and low-fat diet that includes a rich in carbohydrates and proteins.
  2. 1970s: The introduction of a lower cost, low-fat diet that combined low-fat status with a low-fat, low-calorie diet in the 1990s.
  3. 1980s-1990: The development of Tadalafil as a blood pressure-lowering medication.
  4. 1993: The International Patered Federation (IPF) trade show
    1. Cialis (tadalafil) as a blood pressure-lowering medication

C.

As with any drug product, there may be side effects. Generally, patients who experience side effects usually get them within 12 to 24 hours after taking Tadalafil. Side effects usually resolve on their own within 48 hours. Daily Tadalafil use is usually associated with lower incidents and severity of side effects compared to as-needed Tadalafil dosing.

Most common Tadalafil side effects

  • Headache
  • Indigestion
  • Back pain
  • Muscle pain
  • Flushing
  • Stuffy nose

Some more serious side effects have been reported. While rare, it is important to stop taking Tadalafil and contact a doctor right away if any of the following occur:

  • An erection will not go away (priapism). If you have an erection that lasts longer than 4 hours, get medical help right away. If not treated right away, priapism can permanently damage the penis.
  • Sudden vision loss in one or both eyes. Sudden vision loss can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropath (NAION).
  • Sudden hearing decrease or hearing loss. Some may also have ringing in the ears (tinnitus) or dizziness.

For a complete list of possible side effects,.

Possible drug interactions

Some drugs/medications may interact with Tadalafil. You should not take Tadalafil if you are taking nitrates (such as nitroglycerin tablets or patches) because the combination of these with Tadalafil could significantly lower blood pressure and lead to fainting or even death. Additionally, do not take Tadalafil if you are taking Cisapride, other ED medications (e.g. Viagra), Adcirca, or Riociguat.

On your intake form, please be sure to provide AgelessRx with all medications, herbs, non-prescription drugs, or dietary supplements you use. Also be sure to report if you smoke, drink alcohol, or use illegal drugs, as some may interact with your medication.

For a complete list of possible drug interactions,.

Other important safety information

Patients who have a condition called “left ventricular outlet obstruction” from valvular problems or heart muscle enlargement may get side effects such as fainting or light-headedness. Because patients with recent heart attacks or stroke, heart pains (angina), heart failure, uncontrolled blood pressure or uncontrolled irregular heart beats, severe liver disease, and retinal eye problems have not been studied, Tadalafil (Cialis) is not recommended for these patients. There may be rare occurrences of priapism or painful, prolonged erections. This is a serious condition that requires immediate medical attention. Patients should seek prompt medical attention if their erection lasts longer than four hours.

After taking a single tablet, Tadalafil can remain in the body for up to two days. It can remain longer if patients have problems with their kidneys or liver, or they are taking certain other medications.

Note:All information included on this page is a summary. It may not cover all possible information. If you have questions about this medication, talk to a doctor, pharmacist, or healthcare provider.

Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

  1. Choosing sildenafil 5 mg in Canada is a traditional two-page (incomplete) list of medications that you must complete completed in order to complete sildenafil 5 mg in Canada.
  2. Using tadalafil for erectile dysfunction requires completing sildenafil 5 mg complete list of medications in order for tadalafil to work.
  3. Tadalafil 5 mg is used for the treatment of erectile dysfunction (ED) in men aged 18 or over. It is not recommended for patients with severe erectile dysfunction (ED) in patients aged >18 years.
  4. For patients with severe erectile dysfunction (ED) in patients aged >18 years, tadalafil 5 mg is recommended.

The most well-known medicine in the world is thecialis. A long-lasting erection of about 4-6 hours lasts for over a year, and its effect has been a boon for many. But it is also important to know how to use this medicine: it should be taken only with food and water.

When it comes to the best, the most important thing is to make sure that it is safe for you to take the medicine. It should be used only after consulting with a doctor.

There are some medicines that you can take with the help of thes. It is also a good practice to consult with a doctor before you take any medicines. This ensures that you can get an accurate idea of the medicines that you are taking and how to use them.

However, it is not recommended to take the medicine if you are already taking nitrate-containing medicines, and also a medicine that can cause a severe and sometimes fatal problem with the blood flow in your penis.

You can always get the best of both worlds by using thes with the help of a doctor.

A doctor or pharmacist can give you the medicine in a few different ways. For example, they can give you the medication in the form of a prescription. But you must follow their instructions carefully. The first time you use thes you should take the medicine at least 1 hour before you take theThe medicine will be ready for you to take at least 10 minutes after you use it. If you take the medicine in the morning, you can take it at the same time each day.

You should also know that it is not a good idea to take this medicine if you are already taking medicines that are taken with nitrates. The most common medicines that you take with thes are nitrates. Nitrates are used to treat chest pain, and this can cause a serious heart problem. If you take the medicine with nitrate-containing medicines, you will not get the same benefits.

If you take nitrate-containing medicines, you will have a serious blood flow problem. It is very important that you should avoid using them if you are already taking medicines that are taken with the help of theBefore you take thes, you should always follow their instructions carefully. They may say to you: "Take the medicine with water before taking nitrates."

If you are not sure about the medicine, you can consult with your doctor.

If you have a serious medical problem, you must see a doctor immediately.

The most important thing you should know about the medicine is to know what medicines are used. You should also know that you are not taking medicines that can cause a severe and sometimes fatal problem with the blood flow in your penis.Nitrates are used to treat chest pain and other serious problems. This is because nitrates cause a serious blood flow problem. Therefore, if you take nitrate-containing medicines, you will have a serious blood flow problem.

If you are not sure about the medicine, you can consult your doctor.

If you take any of the medicines that you are taking, you should always follow their instructions carefully. The best time to take the medicine is around 30 to 45 minutes after you have taken the medicine. You can take it in the morning, before going to bed, or when you have finished taking the medicine. If you take it after taking the medicine, you may not get the same benefits.

You should also know that it is not a good idea to take the medicine if you are already taking medicines that are taken with the help of the

Product description

Product name:CIALIS

Company name:

DIN:02241803

Status:Marketed

Status date:2022-05-29

Active ingredient(s)Strength
CIALIS (Tadalafil)20 MG

Resources

Click on a resource to visit a page with more information. You may be taken away from this page to a different Government of Canada website.

For consumers
ResourceDescription

The Product Monograph is a scientific document that describes the properties, claims, indications and conditions of use of the product and contains any other information that may be required for optimal, safe and effective use.

The Product Monograph includes three sections:

  • Part I: Health Professional Information;
  • Part II: Scientific Information; and
  • Patient Medication Information

Side effects are troublesome symptoms or feelings that you may not expect that show up when you are taking a medicine.

All suspected side effects should be reported, especially those that are:

  • Unexpected, regardless of their severity, i.e., not consistent with product information or labelling; or
  • Serious, whether expected or not, i.e., that requires being admitted to the hospital, lengthened hospital stay, causes a birth defect, disability, is life-threatening or results in death;
  • Reactions to recently marketed health products (on the market for less than five years), regardless of their nature or severity.
For health care professionals

    Section C.01.020.1 of the Food and Drug Regulations and section 62 of the Medical Devices Regulations, require hospitals to report to Health Canada all serious adverse drug reactions (ADRs) and medical device incidents (MDIs) within 30 days of being documented within the hospital.

    This regulatory requirement only applies to hospitals.

    For researchers
      After Health Canada completes the regulatory review process for a product, the clinical information included in a submission is made publicly available for non-commercial purposes.
      All resources